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Furthermore, in the context of polypharmacy, gastrointestinal side effects may have heightened clinical relevance, underscoring the importance of patient-based risk assessment in clinical practice

Patients with uncontrolled hypertension, active migraine with aura, or severe dehydration risk require closer monitoring during tirzepatide therapy

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Theres emerging evidence that the GIP component improves how fat tissue handles incoming nutrients too, which may be part of why this dual-acting therapy outperforms GLP-1-only drugs head-to-head