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Richie et al (2012), working with age related changes in selenium and glutathione levels in different lobes of the rat prostate found an increased level of oxidative stress together with decreases in selenium and the major cellular antioxidant glutathione (GSH)

Their group also experimentally demonstrated that mice housed at warm ambient temperature (27C) during post-weaning growth have longer limbs than their cold-reared littermates (7C) [24], with the most substantial differences occurring during the active period of postnatal growth

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