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Cabral et al., 2013)

A licensed clinician reviews every intake and decides whether treatment is appropriate eligibility is never automatic

Improved regulation of CBF in response to both transient hyper- and hypotension subsequently protects cerebral microvasculature from hyperperfusive injury and damage as well as ensuring cerebral perfusion is able to match metabolic demand during periods of reduced driving pressures (i.e., orthostatic stress) (Claassen et al., 2021)