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However, disruption in folate metabolism may be the underlying cause of folic acid-responsive NTD, and elevated homocysteine may simply be coincidental

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In June 2022 the UK medicines regulator updated its advice: the MHRA now lists low vitamin B12 as a common side effect of metformin, meaning it can affect up to one in ten people taking it

One of the primary mechanisms postulated to underlie the neurodegenerative effects of CCL11 in long COVID involves the induction of hippocampal microgliosis, leading to diminished neurogenesis and the deterioration of myelinated subcortical axons 27