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Similar improvements in functional and histological healing have been reported across independent rat ligament- and muscle-injury models, synthesized in a 2025 systematic review

The increased secretion of interleukin (IL)-25 by tuft cells following helminth infection has been reported to activate group 2 innate lymphoid cells encouraging subsequent tuft cell proliferation by the secretion of IL-13 (von Moltke et al

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GH promotes sodium and water retention through effects on the kidney, which can cause a puffy appearance in the face, mild swelling in the extremities, and a temporary increase in body weight that reflects water rather than tissue