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Elevated GH even pituitary-derived GH stimulated by secretagogues can worsen insulin sensitivity transiently, particularly in the first 48 weeks of therapy.9 Adults with existing insulin resistance or prediabetes require close glucose monitoring

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After quantifying the concentrations of melatonin, serotonin, dopamine, glutamate, and neurotrophic factors using HPLC and ELISA, the results are analyzed using statistical software such as GraphPad Prism