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RNA Extraction and Quantitative Reverse Transcription-Polymerase Chain Reaction (qRT-PCR) Total RNA was extracted from cellular and cerebral samples using TRIzol reagent (Invitrogen, Carlsbad, CA, United States)

Cleavable linkers can break rapidly in the special environment inside target cells, releasing the drug to achieve efficient killingmaking them especially valuable in strategies requiring fast drug release

However, these pathological changes in the glands were found to be transient upon cessation of the substance