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This is why researchers report benefits lasting 18-24 hours after a single injection despite the peptides being cleared within 4-6 hours

A 2012 study published in Journal of Pharmacology and Experimental Therapeutics demonstrated that a seven-day dihexa dosing protocol produced cognitive improvements in rodent models that persisted for at least 30 days post-treatment, despite the compound being undetectable in plasma within 12 hours of the final dose