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Research indicates that the minimum sodium requirement in adults without active sweating is no more than 115 mg/day, with a safe minimum of approximately 500 mg/day when physical activity and climate are considered

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J Neurosci 19:5629, PMID: 9880576 Dringen R, Gutterer JM, Gros C, Hirrlinger J (2001) Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons