Clinical implication: clinicians should treat vaginal symptoms in patients taking semaglutide as real and addressable , but approach causality cautiously: prioritise common diagnoses (genitourinary syndrome of menopause, infections, dermatologic vulvar disease, STIs, irritant/contact dermatitis, pelvic floor disorders), identify important confounders (notably SGLT2 inhibitors, antibiotics, hormonal therapies), manage symptoms and underlying conditions, and report suspected adverse reactions when there is a reasonable temporal relationship and alternative causes are less likely
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It is also suitable for people who have had gastrointestinal surgeries (like gastric bypass) or have digestive disorders such as Crohns disease, which can impair nutrient absorption
236 According to several cohort studies, evidence showed a higher risk of suffering from gout occurred to the people having western diet when compared to those of having Mediterranean diet
