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Headaches are listed as a common adverse reaction in the UK Summary of Product Characteristics, affecting between 1 in 10 and 1 in 100 patients

Guryanova 1,* , Aliaksandr V

This dimerization appears to induce a switch in intracellular signaling cascades in which administration of a dopamine agonist (quinpirole) alone leads to a rapid increase in Ca 2+ levels, an effect not observed in preparations expressing D2R in the absence of GHSR1a (Kern et al., 2012)