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doi: 10.1371/journal.pgen.1004738 66 RihaK.McKnightT

Programmed-stimuli responsive carrier-free multidrug delivery system for highly efficient trimodal combination therapy

Compared with the PTA and PTK hydrogels, the absorption bands of the C=O and O-H stretch in TA shifted from 1637 to 1714 cm 1 and 3285 to 3326 cm 1 , respectively, indicating the formation of hydrogen bonds between PMI and TA 30

At the same time, Lactobacillus rhamnosus derived extracellular Vesicles can regulate the process of adipocyte metabolism, inhibit the excessive release of inflammatory factors, reduce the chronic inflammatory reaction of adipose tissue, and improve dyslipidemia (Tong et al., 2021)