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Effects on curvature and plaque were not evaluated in the randomized phase but curvature improvements were noted in 23% of patients and plaque reductions in 47% of patients in the open-label phase

It stimulates insulin secretion from pancreatic beta cells, reduces glucagon secretion, slows gastric emptying, and suppresses hepatic glucose production

While rodent studies suggest that BPC 157 interacts with tight junctions to decrease intestinal permeability, we lack any validated human data confirming this effect

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