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The resulting weight reduction often leads to a positive cascade of effects, including better insulin sensitivity and more regular menstrual cycles

Louis say more information is needed on the drugs impact on the body

Sodium-glucose co-transporters are responsible for 97% of glucose reabsorption6 and their inhibition lowers blood glucose by increasing renal glucose excretion.4 , 5 Using SGLT-2 inhibitors increases the risk of DKA6 , 7 by decreasing daily carbohydrate availability by 20%45%,9 lowering endogenous insulin production and stimulating lipolysis that leads to ketogenesis.6 Patients who also receive insulin may decrease insulin doses in response to lower blood glucose patterns, leading to insulin deficiency

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