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Large doses of folic acid given to an individual with an undiagnosed vitamin B 12 deficiency can correct megaloblastic anemia without correcting the underlying vitamin B 12 deficiency, leaving the individual at risk of developing irreversible neurologic damage (21)

Semaglutide primarily affects the earlier step of acid-dependent separation from dietary proteins

Treatment is typically lifelong for patients with pernicious anaemia or irreversible malabsorption conditions

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