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191 Researchers have recognized blood flow shear stress, cytokines, reactive oxygen species, pathogen-associated molecular patterns, and injury-associated molecular patterns as elements that trigger EC inflammation and dysfunction

They have come into the limelight after a large double-blinded study published in NEJM, showed an average 14.9% decrease in weight in obese patients given semaglutide on top of lifestyle modifications, compared to 2.4% in the control arm (see research summary at end)

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Diheptyl Succinate is a natural, "silicone-alternative" emollient that usually comes to the formula with Capryloyl Glycerin/Sebacic Acid Copolymer