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A total of 4 million A375 cells were seeded in a 150-mm dish and, 24 h later, when the tumor cell population reached approximately 10 million, 30 million CD8 + primary human T cells expressing LaccID and a constitutive engineered receptor (TCR or CAR) or T cells expressing only LaccID (no TCR or CAR) were added to the culture, achieving an effector to target ratio of 3:1

Glossary Angiogenesis The formation of new blood vessels from existing vessels

Deferoxamine (DFO) has been shown to preserve dopaminergic neurons in animal models (123)

Phase II clinical trials in patients with sarcoidosis-related small fiber neuropathy demonstrated significant increases in corneal nerve fiber density (a reliable surrogate marker for systemic small fiber health) alongside meaningful reductions in neuropathic pain scores