oasis 1 trial oral semaglutide 50 mg obesity nejm 2023 Can one provide an effective GLP-1 option for PPL with #obesity The P3 for 50mg once daily oral will explore the feasibility and efficacy of this option, likely Drug Watch: The oral version

These findings indicate that while some individuals may observe changes within weeks, the effects are typically minimal and temporary

Common side effects of GLP-1RAs include gastrointestinal reactions such as nausea, vomiting and diarrhea (Wolffenbuttel et al., 2023)

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I find it interesting how few continue beyond 1+ year, and wonder what sort of yo-yo experience that could mean in the future years of benefit programs