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In Phase 3 TRIUMPH-1 data, dysesthesia occurred in 5.1%, 12.3%, and 12.5% of participants taking retatrutide 4 mg, 9 mg, and 12 mg, compared with 0.9% of participants receiving placebo

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A medicine only helps if the patient actually takes it. When looking at the next research steps for elecoglipron, Carroll said he would like to see a phase 3 clinical trial involving thousands of patients over a year or more, to see where the blood-sugar and weight effects actually land and hold

[16] Healthcare professionals can provide individualised advice on symptom management, prescribe appropriate treatments for haemorrhoids, and determine whether specialist referral is indicated