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GLP-1 medications are usually prescribed for people with type 2 diabetes or those with a higher body weight where other methods have not been successful

Excellent review of the complexity of entero-endocrine cell biology, discussing gaps in current understanding and highlighting the translational relevance of entero-endocrine cells in the pathophysiology and therapy of metabolic and inflammatory disorders

Furthermore, many drugs used to treat diabetes, such as SUs, TZDs, and insulin, are associated with weight gain

The practical result is that coverage is either denied outright, buried under impossible prior authorization requirements, or capped with lifetime limits