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Research published in the Journal of Clinical Endocrinology and Metabolism has shown that exercise increases GLP-1 receptor expression and enhances the hormone's effects on appetite regulation and glucose metabolism

[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Li L, Wang H, Zhang J, Sha Y, Wu F, Wen S, He L, Sheng L, You Q, Shi M, Liu L, Zhou H.SPHK1 deficiency protects mice from acetaminophen-induced ER stress and mitochondrial permeability transition

In breast cancer, RNF5 loss is associated with increased ASCT2 expression, finally leading to poor patient outcomes, and poor response to paclitaxel (Jeon et al., 2015)