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Mukherjee KK, Lee AY, Zhu L, Darvas M, & Ladiges W

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Herein, the genetic susceptibility mechanisms of IBD, the specific impacts of environmental and lifestyle factors, and their interactive patterns are systematically reviewed, with particular emphasis on the mechanistic pathways of modifiable factors, with the aim of providing practical guidance for the development of personalized prevention strategies and therapeutic interventions

Most cardiovascular outcome trials and meta-analyses have focused on broader populations with type 2 diabetes and established cardiovascular disease, rather than on patients with isolated coronary microvascular dysfunction [164]