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But better really depends on you Ozempic is a once-weekly injection and works on gut hormones, while Contrave is a daily pill that targets brain pathways, making it potentially more effective if emotional or reward-driven eating is your main struggle

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When added to metformin, the GLP-1 receptor agonists achieve a mean HbA1c reduction of 0.99%,28 together with a significant weight loss (expected 2.9kg on average).40 The GLP-1 receptor agonists do not induce hypoglycemia when administered in monotherapy

J Clin Endocrinol Metab (1990) 71:14216.10.1210/jcem-71-6-1421 56 BarlierAGunzGZamoraAJMorange-RamosIFigarella-BrangerDDufourHet alPronostic and therapeutic consequences of Gs alpha mutations in somatotroph adenomas