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Among them, OPTN and NDP52 can directly bind ubiquitin-tagged mitochondria to the autophagosome through their LC3-interacting regions, even without the involvement of Parkin [132]

Hence, the action of the ascorbateglutathione cycle extends far beyond policing ROS signals, not least because this pathway serves to maintain the reduced states of the ascorbate and glutathione pools that fulfil important but divergent roles in plant biology (Pellny et al

Mazzoli R, Pessione E, Dufour M et al (2010) Glutamate-induced metabolic changes in Lactococcus lactis NCDO 2118 during GABA production: combined transcriptomic and proteomic analysis