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Group 2: Rats received MD (200 mg/kg/day, i.p.) for 10 uninterrupted days followed by a solo MTX dose (20 mg/kg, i.p)
To be eligible to participate in intercollegiate athletics, student-athletes must be both academically and athletically eligible under NCAA rules and regulations
Gastrointestinal effects such as nausea, vomiting, and diarrhea occur frequently, mainly at the start of treatment or after a dose increase
New pain management medications should exhibit higher response rates than existing options and aim to target specific pain pathways while improving understanding of dosing regimens and treatment cycles
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