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10.1016/j.jdermsci.2014.01.011 40 YuN.HuT.YangH.ZhangL.SongQ.XiangF.et al (2020)

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While the relationship between IGF-1 signaling and longevity is complex, with both positive and negative effects saw depending on context, research with IGF1 LR3 has helped clarify the specific effects of receptor start independent of the complex control mechanisms that govern native IGF-1

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