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Collectively, these findings demonstrate that MASLD directly promoted myotube atrophy and that ADM secreted by steatotic hepatocytes acted as a pathogenic signal to impair muscle integrity, providing evidence for hepatokine-mediated livermuscle crosstalk in MASLD-driven sarcopenia

increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle

Response of psoriasis to interleukin-10 is associated with suppression of cutaneous type 1 inflammation, downregulation of the epidermal interleukin-8/CXCR2 pathway and normalization of keratinocyte maturation

Exercise increases the bodys need for water, and staying hydrated helps maintain performance and recovery