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Through its multifaceted effects, such as antioxidant properties, inflammatory modulation, genetic interactions, and RPE function support, zinc supplementation presents a low-cost, accessible option to slow AMD progression and help maintain vision quality in elderly individuals Figure 7

Copper has a complex role in oxidative biology participating in both prooxidant chemistry (where free or weakly bound copper can catalyze damaging reactive-oxygen-species generation) and antioxidant chemistry (as the cofactor of Cu/Zn superoxide dismutase)