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The P3-M treatment group exhibited a significantly higher islet area relative to total pancreas area compared to the P3-M-Sr treatment (p=0.0023, Welchs t-test, 5 n 7), whereas the P3-M-Sr treatment group resembled untreated diabetic controls ( Fig

Seek medical attention if you experience Bloating that worsens progressively over 2+ weeks despite strict dietary compliance Severe abdominal pain that limits daily activities Inability to eat more than a few bites without feeling painfully full Vomiting undigested food 4+ hours after eating No bowel movement for 4+ days despite fiber and hydration Blood in stool or vomit Unexplained fever with abdominal distension Right upper quadrant pain (possible gallbladder involvement) Signs of dehydration (dark urine, dizziness, rapid heart rate) Your healthcare provider may order imaging studies, adjust your semaglutide dose, prescribe prokinetic medications to support gastric emptying, or evaluate for conditions unrelated to semaglutide that may be contributing to the symptoms