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A key feature is its flexible loop 2, which may serve a gating function for substrate binding specificity

For metabolite analysis, excess traditional SOM matrix can produce intense ion adduct peaks in the low MW region, masking metabolite ion signals and limiting quantification sensitivity

Genet Mol Biol 42(1 suppl 1):178185

The use of these technologies in longitudinal care pathways makes it possible to detect individuals at high risk early, resulting in personalised surveillance strategies ( Table 11 )