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To induce quiescence, primary female porcine VICs were cultured on collagen-coated plates (2 g/cm 2 ) in media supplemented with 2% fetal bovine serum (FBS), insulin (5 -2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase r (PKR)-like endoplasmic reticulum kinase (PERK)

Eventually, she became anemic and her hair started to fall out

A very high prevalence of MASLD has been observed among obese individuals, which further strengthens the pathophysiological link between obesity and MASLD [37]

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