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Browning of White Adipose Tissue Third, and perhaps most fascinating, NNMT inhibition promotes browning of white adipose tissue - the conversion of white adipocytes into beige/brown adipocytes that contain numerous mitochondria and express uncoupling protein 1 (UCP1), enabling them to dissipate energy as heat through non-shivering thermogenesis

Research in type 2 diabetes animal models has demonstrated benefits for glucose control parameters and cardiovascular markers in laboratory investigations

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The chart separates that laboratory snapshot from the effect of sustained dosing