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In lupus, SOCS1 function is often impaired, contributing to the uncontrolled immune activation that characterizes the disease

In melanoma, receptor-interacting protein 1 (RIP1) is often upregulated and promotes cancer cell proliferation by activating NF-B

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Khavinson VK, Bondarev IE, Butyugov AA (2003) Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells