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A pilot clinical trial in 12 healthy adults (ages 50-80) found that oral liposomal glutathione (500-1,000 mg/day) produced maximum increases of 40% in whole blood, 28% in plasma, and 100% in peripheral blood mononuclear cells (PBMCs) within two weeks, alongside a 35% reduction in plasma 8-isoprostane, a validated oxidative stress marker

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Cell 3 , 141149 (2003)