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If muscle symptoms are severe or persistent despite these interventions, clinicians should consider laboratory evaluation including creatine kinase, comprehensive metabolic panel with separate magnesium and calcium testing, thyroid function tests, vitamin D levels, and vitamin B12 levels to exclude alternative diagnoses

doi: 10.1038/srep42394 76 ZhangYLiuLJinLYiXDangEYangYet al

The severity and type of rosacea varies by patient, as does the individuals triggers and response to certain treatments

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