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Postulated mechanisms (based on imaging, biomarker studies, neurophysiology and animal models) include remodelling of motor networks, increases in neurotrophic factors, beneficial changes in the gut microbiome, anti-inflammatory effects, synaptic plasticity and improvements in mitochondrial function
Unlike medications that rely on ongoing dosing, bariatric surgery offers a one-time intervention with sustained weight loss results
274 Studies have shown that the expansion of peripheral late-differentiated CD4 + CD28 T cells that produce IFN- after persistent antigenic stimulation is observed in unstable angina
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