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However, if breakouts persist beyond six weeks, appear in unusual locations, or are accompanied by other symptoms like widespread redness or swelling, you're likely experiencing a true adverse reaction rather than purging

Biochem Biophys Res Commun 341:100716 Sanmukhani J, Satodia V, Trivedi J, Patel T, Tiwari D, Panchal B, Goel A, Tripathi CB (2013) Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial

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