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According to the Summary of Product Characteristics (SmPC), these include: Nausea (very common: may affect more than 1 in 10 people) Diarrhoea and constipation (very common) Vomiting and abdominal pain (very common) Decreased appetite and dyspepsia (very common) Most gastrointestinal adverse effects are mild to moderate in severity and tend to diminish over time as the body adjusts to treatment

Caroline Geisler, Ph.D., assistant professor in the University of Kentucky College of Pharmacy Department of Pharmaceutical Sciences, and her team wanted to explore whether a different signaling system in the brain could be targeted to achieve weight loss and blood sugar control without triggering those unpleasant symptoms

"The current data are promising, but we need more evidence before we can reach definitive conclusions," says Dr

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