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Angiogenesis & Blood Flow: TB-500 has been studied for promoting new blood vessel growth, while BPC-157 has been linked with protective effects on vascular tissue

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[Diastolic murmur caused by a phaeochromocytoma (author's transl)]

BPC-157 work centres on local angiogenic signalling, with Hsieh and colleagues (J Mol Med, 2017) reporting VEGFR2 upregulation and internalisation in human endothelial cells, and Chang and colleagues (J Appl Physiol, 2011) reporting increased focal adhesion kinase and paxillin phosphorylation in cultured rat tendon fibroblasts