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The carboxyl side chain of glutamic acid is able to act as a donor and acceptor of ammonia, which is toxic to the body, enabling the safe transport of ammonia to the liver where it is converted to urea and excreted by the kidneys

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If a patients mitochondria are not effectively converting stored fat into usable energy, blocking their appetite will only result in fatigue and muscle catabolism

The observation of cytologically benign changes within a limited tissue sample from such a lesion does not necessarily rule out the presence of adjacent histopathologic atypia