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Both the Wegovy pill and Rybelsus , the oral form of semaglutide approved for type 2 diabetes, should be taken in the same way: In the morning on an empty stomach At least 30 minutes before any food, water, or other medications This could potentially cause problems for patients taking other medications first thing in the morning on an empty stomach, such as levothyroxine (for the treatment of hypothyroidism), says Shannon Fitzgerald, PharmD , a pharmacist, toxicologist, and expert contributor at Drugwatch.com

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Eli Lilly's orforglipron, a daily GLP-1 pill, could be available as soon as next year and would eliminate the need for injections