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Description

Liraglutide-loaded poly (lactic-co-glycolic acid) microspheres: preparation and in vivo evaluation

Phase 2 combination trials reported 35-40% discontinuation rates due to GI side effects when both agents were dosed simultaneously

Daly AF, Beckers A

p27 negatively regulates cell cycle progression by inhibiting the Cyclin-dependent kinase 2 (CDK2)/Cyclin E complex, thereby blocking the G1-to-S phase transition (206)