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The acupoint stimulation activation exerts multimodal analgesic effects through SDH receptor modulation targeting 5-hydroxytryptamine (5-HT) and N -methyl-d-aspartate receptor 1 systems, concurrent -endorphin expression upregulation, and suppression of algogenic neurotransmitter release pathways [122, 123]

And it's quite difficult to distinguish between the symptoms of low folate and high folate (due to potential over supplementation )

I am worried since this is a joint and I dont see how causing trauma to a joint will make it better