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According to the Summary of Product Characteristics (SmPC) approved by the MHRA, gastrointestinal adverse reactions are typically mild to moderate in severity and tend to diminish over time

Common approaches include continuous therapy, 5-days-on/2-days-off protocols, or cycling (e.g., 3-6 months on, 1-2 months off)

Remember that the prescription of off-label medication use should only take place if it's considered the most appropriate treatment for you, and will only be prescribed by your healthcare provider once your other options have also been considered

Our findings suggest a potential impact on calcium levels and pituitary hyperplasia in the GLP1R/GIP network