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Additionally, AC modulated apoptosis-related proteins by downregulating cleaved caspase-3 proteins and upregulating Bcl-2 protein

Additionally, 84-B10 dose-dependently attenuates renal fibrosis and aristolochic acid nephropathy symptoms in murine models, and its low toxicity profiles have demonstrated promising translational potential in preclinical studies [127, 185, 186]

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This narrative review synthesizes current evidence on the roles of key trace elements-iodine, selenium, vitamin D, zinc, iron, copper, and magnesium-in AITD pathogenesis