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It was first studied in the 1990s for its tissue healing and repair properties

Depending on the variation, the MTHFR mutation can inhibit your body from metabolizing up to 70% of folate

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Symptoms Urinary urgency, frequency, and pain in the absence of infection Lower abdominal pressure Pain upon bladder filling or emptying Painful sex Painful orgasm Generalized pelvic pain Nocturia (waking at night to urinate) Symptoms Urinary urgency, frequency, and pain in the absence of infection Lower abdominal pressure Pain upon bladder filling or emptying Painful sex Painful orgasm Generalized pelvic pain Nocturia (waking at night to urinate) Associated Diagnoses IC/PBS is considered a chronic overlapping pain condition (COPC)