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Zepbound (tirzepatide) is similar

Their liraglutide study [36], showed similar findings, with a reduced papilledema risk at 3 months (RR ~ 0.33) that persisted at 24 months (RR ~ 0.52)

This conditional activation provides several advantages in which silent agonists can prime the 7nAChR, making it more responsive to endogenous ACh without causing desensitization typically seen with continuous agonist exposure