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When GLP-1 levels are increased, either through natural production or medication, the following effects occur: Reduced Appetite: GLP-1 interacts with receptors in the brain to reduce hunger signals, leading to decreased food intake

Patients were seen to reduce their weight, and soon the medication was extended to patients desiring weight loss

GLP stands for glucagon like peptide and the receptors for GLP-1 are expressed mainly in pancreatic beta-cells, where its activation can lead to multiple acute and long term effects