Patients with a personal or family history of polycythemia, cardiovascular disease, sleep apnea, or liver dysfunction face elevated risks with testosterone
Patients with Chronic Pulmonary Disease: Hydrocodone bitartrate and acetaminophen tablet-treated patients with significant chronic obstructive pulmonary disease or cor pulmonale, and those with a substantially decreased respiratory reserve, hypoxia, hypercapnia, or pre-existing respiratory depression are at increased risk of decreased respiratory drive including apnea, even at recommended dosages of hydrocodone bitartrate and acetaminophen tablets (see WARNINGS, Life-Threatening Respiratory Depression)
Cauda equina syndrome: If you experience sudden onset of bowel or bladder dysfunction, bilateral leg weakness, or saddle anesthesia (numbness in the groin and inner thighs), this is a surgical emergency
Experiments were performed in triplicates