Problems with iron chelators include: a) Other vital minerals and other substances may be removed b) Deferoxamine and other drugs are toxic to a degree
Blumenthal GM, Bunn PA, Chaft JE, McCoach CE, Perez EA, Scagliotti GV, Carbone DP, HJWL A, Aisner DL, Bergh J, Berry DA, Jarkowski A, Botwood N, Cross DAE, Diehn M, Drezner NL, Doebele RC, Blakely CM, Eberhardt WEE, Felip E, Gianni L, Keller SP, Leavey PJ, Malik S, Pignatti F, Prowell TM, Redman MW, Rizvi NA, Rosell R, Rusch V, de Ruysscher D, Schwartz LH, Sridhara R, Stahel RA, Swisher SG , Taube JM, Travis WD, Keegan P, Wiens JR, Wistuba II, Wynes MW, Hirsch FR, Kris MG
Appelqvist, H., Wster, P., Kgedal, K
As expected, Dox treatment elicited ER stress in cells transduced with Ad-TetOn-NHK, but not in cells expressing Ad-GFP